Jaguar Kicks Off Neonorm Foal TV Campaign & Neonorm Calf Radio
Sales of Neonorm Calf by Jaguar’s Distributor ANIMART Up 167% in
February 2017 Compared to February 2016
Napo Launches National Sales Force for Mytesi
Mytesi Study Abstract Selected for Presentation as Poster Exhibition
at July’s International AIDS Society Conference on HIV Science
SAN FRANCISCO--(BUSINESS WIRE)--Apr. 6, 2017--
Jaguar Animal Health, Inc. (NASDAQ:JAGX) (“Jaguar”), an animal health
company focused on developing and commercializing first-in-class
gastrointestinal products for companion and production animals, foals,
and high value horses, and Napo Pharmaceuticals, Inc. (“Napo”), a human
health company developing and commercializing novel gastrointestinal
prescription products from plants used traditionally in rainforest
areas, today announced the following commercial updates.
Neonorm Sales & Marketing
Jaguar is launching a national TV advertising campaign this month for
Neonorm™ Foal and a radio campaign in key dairy markets for
Neonorm™ Calf. Neonorm™ Foal and Neonorm™
Calf are Jaguar’s lead non-prescription products.
Neonorm™ Foal is a natural, clinically-tested, non-drug
product designed for use as an anti-diarrheal in newborn horses.
Diarrhea is one of the most common clinical complaints in foals,
especially within the first 30 days of life. The crippling effects of
dehydration that often result from secretory diarrhea in foals can
manifest quickly, precipitate adverse health effects and lead to death.
Neonorm™ Calf has been formulated and clinically tested to
help proactively retain fluid in dairy calves and reduce the severity of
diarrhea—aiding calves in avoiding debilitating, dangerous levels of
dehydration associated with scours.
Jaguar’s Neonorm™ Foal TV campaign will consist of a
30-second commercial that will air during evening prime time hours this
month on RFD-TV, a 24-hour television network featuring equine
programming as well as content focused on agribusiness and the rural
lifestyle. The TV spot, which features noted foal medicine specialist
Dr. Siobhan McAuliffe, MVB, DACVIM, can be viewed at https://www.youtube.com/watch?v=f1PzUnKWgHU&feature=youtu.be.
Jaguar’s radio campaign for Neonorm™ Calf consists of a
30-second spot airing this month during early morning hours on
“DairyLine”, a national program regarded as the dairy industry’s
premiere radio voice. On the air for more than 20 years and running on
more than 40 stations across 16 states, “DairyLine” has strong coverage
across all dairy producing regions in the U.S., including Wisconsin,
California and New York. The radio spot can be heard on Jaguar’s blog at https://jaguaranimalhealth.com/dairyline.
The TV and radio ads feature two new contact channels created to help
support sales and build the Neonorm brand: Jaguar’s new Neonorm.com web
address and a new toll-free hotline: 844-NEONORM. In support of sales
efforts, Jaguar also recently created an e-commerce area on the
Company’s corporate website that allows end-user customers to purchase
Neonorm™ Calf and Neonorm™ Foal directly from
Jaguar, and launched a content-filled blog: https://jaguaranimalhealth.com/blog.
Additionally, the Company has been actively targeting dairy farmers,
equine veterinarians, bovine veterinarians, and the owners, breeders and
trainers of horses, via Facebook, Instagram and Twitter during Q1 2017
as part of further efforts to drive exposure, build a community of
engaged followers, and support Neonorm sales. Jaguar also teamed with
ANIMART, LLC, the Company’s dairy market distributor, to conduct “Lunch
n’ Learn” events in Midwest dairy regions in Q1 2017 to help increase
awareness of the benefits and novel mechanism of action of Neonorm™
Calf among ANIMART’s dairy customers.
“The integrated, multichannel marketing initiatives Jaguar has launched
over the past four months in support of Neonorm™ Foal and
Neonorm™ Calf are all aligned with our Neonorm™
commercial strategy of connecting directly with dairy farmers, vets,
horse owners and other members of the equine community, in a targeted
and engaging way, to help build the Neonorm™ brand and drive
sales—both directly and through our core dairy market distributor,
ANIMART, and our exclusive distributor for Neonorm™ Foal,
Henry Schein,” commented Lisa Conte, Jaguar’s president and CEO.
ANIMART sales of Neonorm™ Calf, measured by the total number
of Neonorm™ Calf boluses sold, are up 167% for February 2017
compared to February 2016.
Neonorm™ is a standardized botanical extract derived from the Croton
lechleri tree that acts at the same last step in a physiological
pathway generally present in mammals. Foaling season in the northern
hemisphere generally runs from May through September, while calf scours
season in the U.S. generally runs from March through June.
Napo Launches National Sales Force to Promote and Provide Samples of
Mytesi™ to HIV Healthcare Providers
As announced February 28, 2017, Napo has signed an agreement with Alamo
Pharma Services, Inc. for the establishment and management of a national
sales team for Mytesi™. The launch of the sales force took
place this week. Mytesi™, launched by Napo in October 2016,
is approved by the U.S. FDA for the symptomatic relief of noninfectious
diarrhea in adults with HIV/AIDS on antiretroviral therapy. Alamo is
providing a team of shared sales representatives to supplement the
dedicated Napo representatives to promote and sample Mytesi™
in key metropolitan areas throughout the United States. The sales
representatives have begun reaching out to doctors who have large
populations of HIV patients and, therefore, are high-volume prescribers
of antiretroviral therapies.
Napo and Jaguar estimate the potential U.S. market for Mytesi™
to be approximately $100 million in gross annual sales, and forecast
that Mytesi™ will generate approximately $7.0 million in net
sales in 2017, with the greatest impact on prescription growth
coincident with the deployment of the sales force and sampling program.
Mytesi™ Study Abstract Selected for
Presentation as a Poster Exhibition at the 2017 International AIDS
Society Conference on HIV Science
An abstract based on new crofelemer (Mytesi™) data from a
supplemental analysis of the Napo-sponsored ADVENT trial has been
accepted for presentation as a poster exhibition at the 9th IAS
Conference on HIV Science (IAS 2017), to be held in Paris, France, July
Canalevia™ for Use in Dogs with
Chemotherapy-Induced Diarrhea (CID)
As previously announced, Jaguar expects Canalevia™ for the
indication of CID in dogs to be the Company’s first drug product
candidate available commercially. Pending FDA approval of Canalevia™
for CID, Jaguar expects to conduct the commercial launch of Canalevia™
for this indication in the next year. Jaguar’s lead drug product
candidate, under investigation for various types of diarrhea in dogs,
Canalevia™ is a canine-specific formulation of crofelemer, an
active pharmaceutical ingredient isolated and purified from the Croton
lechleri tree, which is sustainably harvested. Numerous animal and
human clinical trials have shown significant beneficial results in the
use of crofelemer in the treatment of secretory diarrhea.
As announced March 31, 2017, Jaguar and Napo have entered a definitive
merger agreement. The proposed merger remains subject to customary
conditions to closing. Upon the consummation of the merger, Jaguar’s
name will be changed to Jaguar Health, Inc., and Napo will operate as a
wholly-owned subsidiary of Jaguar, focused on human health. Subject to
the conditions to closing, the proposed merger is expected to close
during the second quarter of 2017.
Mytesi™ (crofelemer 125mg delayed-release tablets) is an
antidiarrheal indicated for the symptomatic relief of noninfectious
diarrhea in adult patients with HIV/AIDS on antiretroviral therapy
(ART). Mytesi™ is not indicated for the treatment of
infectious diarrhea. Rule out infectious etiologies of diarrhea before
starting Mytesi™. If infectious etiologies are not
considered, there is a risk that patients with infectious etiologies
will not receive the appropriate therapy and their disease may worsen.
In clinical studies, the most common adverse reactions occurring at a
rate greater than placebo were upper respiratory tract infection (5.7%),
bronchitis (3.9%), cough (3.5%), flatulence (3.1%), and increased
bilirubin (3.1%). Please see complete Prescribing Information
available at Mytesi.com
About Napo Pharmaceuticals, Inc.
San Francisco-based Napo Pharmaceuticals, Inc. focuses on the
development and commercialization of proprietary pharmaceuticals for the
global marketplace in collaboration with local partners.
For more information, please visit www.napopharma.com.
About Jaguar Animal Health, Inc.
Jaguar Animal Health, Inc. is an animal health company focused on
developing and commercializing first-in-class gastrointestinal products
for companion and production animals, foals, and high value horses.
Canalevia™ is Jaguar’s lead prescription drug product
candidate, intended for the treatment of various forms of diarrhea in
dogs. Equilevia™ (formerly referred to as SB-300) is Jaguar’s
prescription drug product candidate for the treatment of
gastrointestinal ulcers in horses. Canalevia™ and Equilevia™
contain ingredients isolated and purified from the Croton lechleri
tree, which is sustainably harvested. Neonorm™ Calf and
Neonorm™ Foal are the Company’s lead non-prescription
products. Neonorm™ is a standardized botanical extract
derived from the Croton lechleri tree. Canalevia™ and
Neonorm™ are distinct products that act at the same last step
in a physiological pathway generally present in mammals. Jaguar has nine
active investigational new animal drug applications, or INADs, filed
with the FDA and intends to develop species-specific formulations of
Neonorm™ in six additional target species, formulations of
Equilevia™ in horses, and Canalevia™ for cats and
For more information about Jaguar, please visit www.jaguaranimalhealth.com.
Additional Description of the Proposed Merger
As announced March 31, 2017, Jaguar and Napo Pharmaceuticals, Inc.
(“Napo”) have entered a definitive merger agreement (the “Agreement”).
Upon the consummation of the merger, Jaguar’s name will be changed to
Jaguar Health, Inc., and Napo will operate as a wholly-owned subsidiary
of Jaguar, focused on human health. Following consummation of the
proposed merger, it is expected that there will be approximately 65
million shares outstanding in the combined entity. The balance of the
outstanding fully diluted equity of the combined entity, when factoring
in convertible debt, is expected to be approximately 93 million shares
following consummation of the proposed merger. These share counts are
based on a relative company valuation, per the merger terms, of Napo to
Jaguar of approximately 3:1.
Important Additional Information will be Filed with the SEC
This press release may be deemed solicitation material regarding the
intended merger between Jaguar and Napo. Jaguar currently intends to
file with the SEC a Registration Statement on Form S-4 that will include
a proxy solicitation. Jaguar also plans to file other relevant materials
with the SEC. Stockholders of Jaguar and Napo are urged to read the
proxy solicitation/prospectus contained in the Registration Statement
when it becomes available and any other relevant materials filed with
the SEC because these materials will contain important information about
the potential merger. Once available, these materials will be made
available to the stockholders of Jaguar and Napo at no expense to them.
The Registration Statement, proxy statement/prospectus and other
relevant materials, including any documents incorporated by reference
therein, once available, may be obtained free of charge at the SEC’s
website at www.sec.gov
or from Jaguar at www.jaguaranimalhealth.com
or by emailing email@example.com.
Jaguar and certain of its directors and executive officers may be deemed
to be participants in the solicitation of proxies in connection with the
potential merger. Information about the executive officers and directors
of Jaguar is set forth in Jaguar’s Annual Report on Form 10-K for the
fiscal year ended December 31, 2016 as filed with the SEC on February
15, 2017 and Definitive Proxy Statement for the 2016 Annual Meeting of
Stockholders of Jaguar filed with the SEC on April 29, 2016.
Notice as to Unregistered Securities
In connection with the intended merger, shares of common stock and other
securities of Jaguar have been and will be offered to accredited
institutional and individual investors pursuant to one or more
exemptions from registration under the Securities Act of 1933, as
amended (the “Securities Act”). These securities have not been
registered under the Securities Act or the securities laws of any other
jurisdiction and may not be offered or sold in the U.S. absent
registration or an applicable exemption from registration requirements.
Certain statements in this press release constitute “forward-looking
statements.” These include statements regarding Napo’s and Jaguar’s
estimate that the potential U.S. market for Mytesi™ is
approximately $100 million in gross annual sales, Napo’s and Jaguar’s
forecast that Mytesi™ will generate approximately $7.0
million in net sales in 2017, with the greatest impact on prescription
growth coincident with the deployment of the sales force and sampling
program, Jaguar’s expectation that Canalevia™ for the
indication of CID in dogs will be the Company’s first drug product
candidate available commercially, and that, pending FDA approval of
Canalevia™ for CID, Jaguar expects to conduct the commercial
launch of Canalevia™ for this indication in the next year,
the structure, timing and completion of the proposed merger or Napo debt
settlement, expectations regarding the capitalization, resources and
ownership structure of the combined company, the expectation that the
merger conditions to closing will be satisfied, Jaguar’s intention to
develop species-specific formulations of Neonorm™ in
additional target species, and the Company’s plan to develop
formulations of Canalevia™ for cats, horses and dogs. In some
cases, you can identify forward-looking statements by terms such as
“may,” “will,” “should,” “expect,” “plan,” “aim,” “anticipate,” “could,”
“intend,” “target,” “project,” “contemplate,” “believe,” “estimate,”
“predict,” “potential” or “continue” or the negative of these terms or
other similar expressions. The forward-looking statements in this
release are only predictions. Jaguar has based these forward-looking
statements largely on its current expectations and projections about
future events. These forward-looking statements speak only as of the
date of this release and are subject to a number of risks, uncertainties
and assumptions, some of which cannot be predicted or quantified and
some of which are beyond Jaguar’s control. Except as required by
applicable law, Jaguar does not plan to publicly update or revise any
forward-looking statements contained herein, whether as a result of any
new information, future events, changed circumstances or otherwise.
View source version on businesswire.com: http://www.businesswire.com/news/home/20170406005574/en/
Source: Jaguar Animal Health, Inc.
KCSA Strategic Communications
Garth Russell, 212-896-1250